Natural Factors Natural Factors - Glycine 5g, 450 g

Price

Regular Canadian retail price: $33.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.

In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.

See member pricing on Natural Factors Natural Factors - Glycine

Why people keep reordering it

Best suited to: wants the bedtime glycine dose without capsules, buys collagen mainly for the glycine, takes 10 g a day or more and hates pills.

What the research supports

Each scoop is 5 g of fermented free-form glycine, the only ingredient. Label range is 1 to 3 scoops a day, so the tub lasts 30 to 90 days.

Sleep trials use about 3 g of glycine before bed.

Blood glucose (evidence: mixed, from small randomized controlled trial, observational)

People with poorer glucose control tend to run lower on plasma glycine, which is one clue it plays a role in how the body handles glucose. Small supplementation trials have gone both ways on whether adding it back moves glucose markers.

Sleep (evidence: limited, from randomized crossover trial)

Glycine is thought to lower core body temperature and quiet the nervous system before sleep. Crossover trials using 3 g before bed found people fell asleep faster and rated next-day alertness higher, though each study was only a dozen or so people.

Collagen synthesis (evidence: limited, from randomized crossover trial)

Collagen is roughly a third glycine by weight, and dietary supply can be the limiting factor in how much the body makes. Human trials showing that supplemental glycine changes skin or connective tissue directly are still thin.

Muscle growth (evidence: limited, from randomized crossover trial)

Muscle protein synthesis is triggered mainly by essential amino acids like leucine, and glycine is not one of them. It adds to total amino intake, but will not by itself build muscle or strength.

Read the literature: Blood glucose on PubMed, Sleep on PubMed, Collagen synthesis on PubMed, Muscle growth on PubMed.

Is it right for you

Worth it if

Wants the bedtime glycine dose without capsules

One 5 g scoop covers the 3 g used in the sleep trials, and glycine dissolves clear in plain water.

Buys collagen mainly for the glycine

Glycine is close to a third of collagen's amino acid content, so 5 g of pure glycine delivers more of it than a 10 g collagen scoop, for far less per gram.

Takes 10 g a day or more and hates pills

At 5 g per scoop, a 15 g daily intake is three scoops instead of thirty capsules.

Look elsewhere if

Wants an amino acid that actually drives muscle growth

Leucine-rich whey protein or a full essential amino acid blend does that job. Glycine is non-essential and your body already makes some.

Wants a reliable wind-down that works the first night

Magnesium bisglycinate or L-theanine are better-studied first stops, and the glycine sleep trials are small enough that it may do nothing for you.

Only needs a gram or two a day

A 500 mg capsule is easier to dose accurately than eyeballing a fifth of a scoop.

What to expect

If you notice anything, it will be on sleep, and it shows up the same night or not at all. People in the trials fell asleep faster and rated themselves less groggy the next morning rather than feeling sedated. Everything else glycine does, feeding collagen synthesis and glucose handling, happens quietly with nothing to feel.

How it compares

Compared with glycine capsules

5 g per scoop instead of 500 mg per capsule, so a research-sized dose is one scoop rather than six to ten capsules, and the cost per gram in a 450 g tub is a fraction of the capsule price. The tradeoff: You have to mix it into liquid every time, and a scoop is an approximation rather than a measured 5.00 g.

Compared with a collagen peptide powder

Pure glycine, so you know exactly which amino acid you are taking and how much of it. The tradeoff: You lose the proline, hydroxyproline and peptide fractions that the collagen research actually tested.

Product details

Active ingredient

Glycine

Ingredient form

g

Strength

5g

Suggested use

1 scoop (approx. 5 g) 3 times daily or as directed by a health care practitioner. Mix product in enough liquid (water, juice, etc.) to ensure that the powder is drinkable immediately before consumption. Consult a health care practitioner for use beyond 3 months.

Independent testing

ISURA

Certifications

Non-GMO

Storage

Store in a cool, dry place

Brand

Natural Factors

How to take it

1 scoop (approx. 5 g) 3 times daily or as directed by a health care practitioner. Mix product in enough liquid (water, juice, etc.) to ensure that the powder is drinkable immediately before consumption. Consult a health care practitioner for use beyond 3 months.

• Store in a cool, dry place away from direct light.
• Keep out of reach of children.
• Consult a practitioner if you are pregnant, nursing or on medication.

Ingredients

Free from

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or genetically modified genes or proteins. Suitable for vegetarians/vegans.

Interactions and cautions

Medications

May interact with certain prescription medications. Review with your pharmacist if you take daily medication.

Timing

Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.

Pregnancy and breastfeeding

Consult a healthcare practitioner before use if pregnant or breastfeeding.

General

Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.

This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.

Questions about Natural Factors - Glycine

Is this the genuine, authentic product?

Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.

How is the price below retail?

We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.

How fast does it ship?

Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.

Can I return it?

You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.