Preferred Nutrition Preferred Nutrition - Berberine 500mg, 120 vcap

Preferred Nutrition Berberine - 500 mg - A naturally occurring compound from a variety of plants such as barberry, goldenseal and Oregon grape that helps to maintain healthy glucose metabolism and cardiovascular health. Clinical studies have shown that 500 mg of Berberine supports weight management by lowering blood sugar and minimizing the production of insulin, the fat-storing hormone.

Preferred Nutrition Preferred Nutrition - Berberine 500mg, 120 vcap

Price

Regular Canadian retail price: $36.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.

In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.

See member pricing on Preferred Nutrition Preferred Nutrition - Berberine 500mg

Why people keep reordering it

Best suited to: someone who eats two solid meals a day, people focused on normal glucose metabolism, anyone who wants berberine alone, not a blend.

What the research supports

Each capsule is 500 mg of berberine hydrochloride, taken twice daily with meals for 1,000 mg a day. The 120 capsule bottle lasts 60 days at that dose.

Trials use 1,000 to 1,500 mg a day, split 2 to 3 times.

Glucose metabolism (evidence: moderate, from randomized controlled trial, meta-analysis)
Berberine activates AMPK, the enzyme cells use to pull glucose from the blood when energy runs low, and trials at 1,000 to 1,500 mg a day lower fasting glucose.
Blood lipids (evidence: moderate, from randomized controlled trial, meta-analysis)
Pooled trials of berberine at around 1 gram a day show modest reductions in total cholesterol and triglycerides, both markers tied to cardiovascular strain.
Body weight (evidence: limited, from randomized controlled trial)
Weight change with berberine is small and inconsistent, typically a kilogram or two over twelve weeks, and usually alongside diet changes that account for part of it.
Gut bacteria (evidence: limited, from randomized controlled trial)
Very little berberine is absorbed, so most of it stays in the gut and shifts which bacteria live there, though what that shift means for a person is unclear.

Read the literature: Glucose metabolism on PubMed, Blood lipids on PubMed, Body weight on PubMed, Gut bacteria on PubMed.

Is it right for you

Worth it if

someone who eats two solid meals a day
the dose is designed to split 500 mg with each meal, so a two meal pattern fits it without extra reminders.
people focused on normal glucose metabolism
AMPK activation is the berberine mechanism with the most human data behind it, at roughly this daily amount.
anyone who wants berberine alone, not a blend
500 mg of berberine HCl per capsule with no chromium, cinnamon or bitter melon padding the label out.

Look elsewhere if

someone buying it mainly to lose weight
weight changes in berberine trials are small, a kilogram or two across twelve weeks. Money spent on protein intake and a soluble fibre supplement moves appetite further.
anyone taking something daily
check with a practitioner before starting rather than after. Berberine slows the liver enzymes that clear a long list of common compounds, which can push their blood levels up.
people with an easily upset stomach
cramping, loose stools and constipation are the usual complaints at 1000 mg. Start with one capsule at the largest meal, or look at a dihydroberberine product, which reaches similar blood levels from a smaller amount of powder in the gut.

What to expect

Digestive grumbling in the first week is the thing people actually notice, and it usually settles. Everything else is invisible without testing: the changes measured in trials showed up on bloodwork at eight to twelve weeks, not in how anyone felt.

How it compares

Compared with a blended blood sugar formula with chromium and cinnamon
you get the full 500 mg of berberine per capsule that the trials used, rather than 100 mg of it buried behind a proprietary blend. The tradeoff: no chromium, no cinnamon, and two capsules timed to meals is a stricter routine than one blend capsule with breakfast.
Compared with berberine phytosome or dihydroberberine
plain berberine HCl is the form nearly all the human research used, so 500 mg here maps directly onto published doses instead of requiring a conversion. The tradeoff: berberine HCl absorbs poorly, under 1 percent, which is exactly why the dose has to be this large and split across meals. Enhanced forms get there on less powder and are gentler on the gut.

Product details

Active ingredient
Berberine (hydrochloride) (Berberis vulgaris) (root bark)
Ingredient form
vcap
Strength
500 mg
Servings per container
120
Suggested use
Take 1 capsule 2 times daily with meals or as directed by a health care practitioner.
Country of manufacture
Canada
Independent testing
ISURA
Certifications
Non-GMO, Made in Canada
Storage
Store in a cool, dry place
Brand
Preferred Nutrition

How to take it

Take 1 capsule 2 times daily with meals or as directed by a health care practitioner.

  • Store in a cool, dry place away from direct light.
  • Keep out of reach of children.
  • Consult a practitioner if you are pregnant, nursing or on medication.

Ingredients

Each vegetarian capsule contains

Berberine (hydrochloride) (Berberis vulgaris) (root bark)
500 mg

Non-medicinal ingredients

Vegetarian capsule (carbohydrate gum, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acids.

Free from

Contains no artificial preservatives, colours or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Interactions and cautions

Medications
May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
Timing
Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
Pregnancy and breastfeeding
Consult a healthcare practitioner before use if pregnant or breastfeeding.
General
Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.

This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.

Questions about Preferred Nutrition - Berberine 500mg

Is this the genuine, authentic product?
Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
How is the price below retail?
We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
How fast does it ship?
Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
Can I return it?
You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.