Sisu Sisu - Vitamin B6 100mg, 60 vcaps
Sisu Vitamin B6 - Vitamin B6 has proven useful in the treatment of high blood pressure, hyperactivity and PMS, and maintaining optimal levels of Vitamin B6 in the body has shown to be effective in reducing the risk of cardiovascular disease. It has also shown to be beneficial to brain functions, immune system support and skin problems. B6 plays an important role in the body's ability to absorb Vitamin B12 and in the production of hydrochloric acid and magnesium, as well as in the breakdown and utilization of carbohydrates, fats and proteins.

Price
Regular Canadian retail price: $11.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Active methylated forms
- B vitamins in the forms your body can put to use right away.
- Mood and hormone balance
- Supports healthy methylation, mood and hormonal rhythm.
- Energy at the cellular level
- Feeds the pathways behind steady, real energy.
Best suited to: someone told to take b6 on its own, high protein intake and heavy training, working on homocysteine alongside folate and b12.
What the research supports
One vegetarian capsule holds 100 mg of pyridoxine hydrochloride, roughly sixty times a typical daily need. Sixty capsules last about two months at one a day.
Studies use 25 to 50 mg a day.
- Tissue repair (evidence: strong, from human metabolic studies, depletion and repletion trials)
- B6 is the cofactor enzymes need to break apart and rebuild amino acids from food, so a shortfall can slow how quickly your body repairs tissue and makes new enzymes.
- Tiredness (evidence: strong, from human metabolic studies, depletion and repletion trials)
- Your body needs B6 to make the pigment that goes into red blood cells. Running low can leave you feeling drained without an obvious reason.
- Heart health (evidence: moderate, from randomized controlled trial, meta-analysis)
- B6 handles one step in clearing a compound linked to artery damage from the blood, though it plays a smaller role than folate and B12 in that process.
Read the literature: Tissue repair on PubMed, Tiredness on PubMed, Heart health on PubMed.
Is it right for you
Worth it if
- someone told to take B6 on its own
- this is plain pyridoxine hydrochloride with no other B vitamins riding along, so you can hit a specific B6 amount without changing anything else you take.
- high protein intake and heavy training
- B6 is the cofactor for the transaminase enzymes that shuttle amino groups around, so people eating and metabolizing a lot of protein have a higher functional B6 requirement than the RDA suggests.
- working on homocysteine alongside folate and B12
- B6 runs the transsulfuration arm of that pathway, and 100 mg is comfortably enough to saturate it.
Look elsewhere if
- anyone wanting general B vitamin coverage
- a B complex or a multivitamin with 25 to 50 mg of B6 makes more sense, because B vitamins work as a set and 100 mg of B6 alone every day is far more than a general top-up calls for.
- someone pregnant looking at B6 for nausea
- the approach studied there uses about 10 to 25 mg spread across three doses a day, so a single 100 mg capsule is the wrong shape for it and should be practitioner-directed anyway.
- someone who wants the ready-to-use coenzyme form
- pyridoxal-5-phosphate, usually sold around 20 to 50 mg, skips the liver conversion step this form needs.
What to expect
Nothing you can feel. B6 is a cofactor, so at a normal intake it is already doing its job and more of it does not produce a sensation. If a practitioner has you on it for a specific reason, judge it over six to eight weeks, and stop and check in if you notice tingling in your hands or feet.
How it compares
- Compared with a 50 mg B complex
- you get double the B6 with no thiamine, riboflavin, niacin or B12 competing for space, which is what you want when B6 is the only variable you are changing. The tradeoff: you get none of the other B vitamins, and running 100 mg of B6 for months without B12 and folate alongside it is a lopsided way to supplement.
- Compared with pyridoxal-5-phosphate capsules
- pyridoxine hydrochloride is the form used in most of the human research and costs noticeably less per capsule. The tradeoff: your liver has to phosphorylate it before it does anything, a step the P5P form has already done for you.
Product details
- Active ingredient
- Vitamin B6 (pyridoxine hydrochloride)
- Ingredient form
- vcaps
- Strength
- 100 mg
- Servings per container
- 60
- Suggested use
- Take 1 capsule daily or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- independent third-party labs
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Sisu
How to take it
Take 1 capsule daily or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetarian capsule contains
- Vitamin B6 (pyridoxine hydrochloride)
- 100 mg
Non-medicinal ingredients
Microcrystalline cellulose, magnesium stearate (vegetable), stearic acid (vegetable), silicon dioxide. Capsule Shell: Hypromellose.
Free from
Contains no dairy, wheat, gluten, corn, or soy. Suitable for a vegan diet.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Sisu - Vitamin B6 100mg
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.