Sisu Sisu - Ester-C Supreme, 120 vcaps
Sisu Ester-C Supreme Citrus Free - A powerful, immune system enhancing complex designed specifically for those who suffer from allergies, and desire the immune-boosting qualities of patented Ester-C. Sisu Ester-C Supreme is a combination of Ester-C, combined with Polysaccharides and Bioflavonoids, designed to work synergistically to effectively fight invading organisms, and provide maximum bio-availability and absorption. Can be taken as a preventative measure, or to reduce the severity and duration of colds and flus.

Price
Regular Canadian retail price: $41.48 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Year-round defense
- Daily support for a resilient immune response.
- Antioxidant support
- Helps protect cells from everyday oxidative stress.
- Tradition meets research
- Time-tested ingredients in clinically informed doses.
Best suited to: people who react to citrus, sensitive stomachs on plain vitamin c, anyone wanting one capsule to cover the day.
What the research supports
Each capsule is 600 mg of vitamin C as calcium ascorbate, built citrus-free unlike Sisu's other Ester-C capsules. The bottle of 120 lasts two to four months.
Studies use 200 mg or more a day.
- Immunity (evidence: strong, from randomized controlled trial, review)
- White blood cells hold vitamin C at many times the concentration found in blood plasma and need it to work properly, and that internal store runs down when your immune system is active.
- Collagen formation (evidence: strong, from randomized controlled trial, review)
- The two enzymes that build collagen from proline and lysine cannot run without vitamin C, so skin, cartilage and gum tissue cannot cross-link properly when intake falls short.
- Antioxidants (evidence: limited, from randomized controlled trial)
- Quercetin needs to reach a certain blood level to have any measurable antioxidant effect, and human reports of that start around 500 mg a day, ten times the 50 mg in this capsule.
- Immune response (evidence: limited, from randomized controlled trial)
- Human trials on larch arabinogalactan used gram-level daily doses over several weeks and found modest, inconsistent results even then, well above the 100 mg here.
Read the literature: Immunity on PubMed, Collagen formation on PubMed, Antioxidants on PubMed, Immune response on PubMed.
Is it right for you
Worth it if
- People who react to citrus
- There is no lemon, orange, mandarin or grapefruit peel anywhere in this formula, which is unusual for a bioflavonoid style vitamin C.
- Sensitive stomachs on plain vitamin C
- Calcium ascorbate is close to neutral pH, so a 600 mg dose does not arrive as acid.
- Anyone wanting one capsule to cover the day
- 600 mg in a single capsule already sits above the point where plasma vitamin C plateaus, so a second is optional.
Look elsewhere if
- Someone buying it for the quercetin
- 50 mg is a tenth of what quercetin studies have used. A standalone quercetin at 500 mg per dose is the honest way to get it.
- Someone buying it for the arabinogalactan
- The human work used 1.5 to 4.5 g a day, which means a powdered fibre scoop, not 100 mg tucked into a capsule.
- Anyone with no citrus problem at all
- A standard buffered vitamin C with citrus flavonoids delivers the same 600 mg for less, and comes in bottles twice this size.
What to expect
Nothing you can feel. If you landed here because citrus flavonoids did not agree with you, the only thing you should notice is the absence of that reaction, within the first few days.
How it compares
- Compared with a standard buffered vitamin C with citrus bioflavonoids
- It takes citrus out completely and puts berry anthocyanidins, quercetin and larch arabinogalactan in its place, so the flavonoid content comes from a different plant family. The tradeoff: More per capsule, 120 in the bottle instead of 240, and all three additions sit well below their studied amounts. The reason to choose this is the citrus free formula, not the extras.
Product details
- Medicinal ingredients
- Vitamin C (from Ester-C brand calcium ascorbate), Multianthocyanidins (berry/fruit*), Quercetin (fruit)
- Ingredient form
- vcaps
- Servings per container
- 120
- Suggested use
- Take 1-2 capsules daily or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- independent third-party labs
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Sisu
How to take it
Take 1-2 capsules daily or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetarian capsule contains
- Vitamin C (from Ester-C brand calcium ascorbate)
- 600 mg
- Arabinogalactan (Larix occidentalis/Larix laricina) (bark/stem) ResistAid brand
- 100 mg
- Multianthocyanidins (berry/fruit*)
- 50 mg
- Quercetin (fruit)
- 50 mg
black currant (Ribes nigrum), cranberry (Vaccinium macrocarpon), blueberry (Vaccinium corymbosum), bilberry (Vaccinium myrtillus).
Non-medicinal ingredients
Magnesium stearate (vegetable). Capsule shell: Hypromellose.
Free from
Contains no dairy, wheat, gluten, peanuts or soy.
Interactions and cautions
- Medications
- Some immune botanicals may interact with immunosuppressant medication. Review with your practitioner.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Sisu - Ester-C Supreme
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.