Pure Encapsulations Pure Encapsulations - Liver-G.I. Detox, 60 caps
Pure Encapsulations Liver-G.I. Detox - Formulated to help support gastrointestinal health and function of the liver, an organ involved in detoxification. Silymarin supports the liver by enhancing phase II detoxification enzymes, supporting glutathione synthesis and promoting liver cell functions. With the amino acids glutamine, glycine and taurine, methionine is a lipotropic compound that enhances healthy hepatic function by supporting lipid metabolism and glutathione concentration. Alpha lipoic acid is a water- and fat-soluble antioxidant, which allows it to function in almost any part of the body, including the liver. NAC is a precursor to glutathione, and supplemental NAC increases tissue levels of glutathione. This formula also offers sulforaphane, an important metabolite from broccoli sprout concentrate, along with turmeric, which has a long history of use for providing broad-spectrum support. Artichoke extract is used in Herbal Medicine to help relieve digestive disturbances and increase bile flow, providing aid to the digestive process. Chlorella, the most studied –green food,– is traditionally celebrated for its beneficial health properties.

Price
Regular Canadian retail price: $47.28 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
Currently out of stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Pure Encapsulations Pure Encapsulations - Liver-G.I. Detox
Why people keep reordering it
- Cartilage and connective tissue
- Supports the structures that keep joints moving comfortably.
- Mobility and recovery
- For active bodies and everyday wear alike.
- Skin, hair and nails too
- Collagen support that shows beyond the joints.
Best suited to: heavy or fatty meals sit badly, want the gut and liver sides in one bottle, testing a direction before committing.
What the research supports
Three capsules a day give 187.5 mg of artichoke leaf extract and 337.5 mg of L-glutamine for the gut lining. The bottle lasts 20 days.
Artichoke leaf trials use 320 to 640 mg a day.
- Digestive comfort (evidence: moderate, from randomized controlled trial)
- Artichoke leaf increases bile flow, which helps break down fat in a meal, and trials at 320 mg and up report less bloating and discomfort afterward.
- Bile acids (evidence: limited, from )
- Taurine is one of the building blocks the liver uses to make bile acids that digest fat, but there is little human trial work testing that process directly in unstressed people.
- Glutathione (evidence: moderate, from randomized controlled trial)
- NAC and methionine both feed the pathway your liver uses to make glutathione, its main detox antioxidant, though trials showing a clear rise use several times the 150 mg of NAC here.
- Liver enzymes (evidence: mixed, from randomized controlled trial, meta-analysis)
- Milk thistle's silymarin is thought to shield liver cells from oxidative damage, but trials disagree with each other, and the ones showing benefit generally use several times this extract amount.
Read the literature: Digestive comfort on PubMed, Bile acids on PubMed, Glutathione on PubMed, Liver enzymes on PubMed.
Is it right for you
Worth it if
- Heavy or fatty meals sit badly
- Artichoke leaf is the bile flow ingredient with actual trial support for post meal discomfort, and it is paired here with taurine, which the body uses to conjugate bile acids.
- Want the gut and liver sides in one bottle
- Glutamine, glycine and taurine work the intestinal and bile end while milk thistle, NAC and lipoic acid work the liver end, a split most single purpose formulas do not attempt.
- Testing a direction before committing
- Twelve ingredients at modest doses is a reasonable way to learn which lever helps you before paying for a full dose single active.
Look elsewhere if
- Persistent or worsening digestive symptoms
- Symptoms that keep coming back deserve a proper workup and a cause, not a 20 day bottle of a blend.
- Reacts to the daisy family
- Milk thistle and artichoke are both in that family and the label rules this out. Plain glutamine, glycine and taurine cover the amino acid side with no botanicals.
- Wanting real support for the gut lining
- L-glutamine powder at 5 g a day is the dose that research uses. Three capsules here give 337.5 mg.
What to expect
The label asks for three weeks of use before judging it, which is honest. What people report first, if anything, is heavier meals sitting easier within a week or two, which would be the artichoke and taurine. There is no perceptible liver effect to wait for.
How it compares
- Compared with a standalone milk thistle capsule
- The amino acids and artichoke give this a digestive and bile angle that milk thistle on its own has nothing to say about. The tradeoff: The milk thistle itself is at a fraction of a standalone dose, and 60 capsules at three a day runs out in under three weeks.
- Compared with the brand's mineral and pectin antioxidant blend
- This one is built for the gut and bile end, with glutamine, artichoke and a much heavier amino acid load. The tradeoff: It drops the selenium, zinc and 1,000 mcg of sulforaphane that the other formula uses for antioxidant defence.
Product details
- Medicinal ingredients
- DL-Alpha-Lipoic Acid, N-AcetylL-cysteine, Turmeric Root Extract, Milk thistle Seed Extract and 8 more
- Ingredient form
- caps
- Servings per container
- 60
- Suggested use
- Adults: Take 3 capsules daily with a meal, a few hours before or after taking other medications or health products, or as directed by a healthcare practitioner. Drink plenty of water while taking this product. Use for a minimum of 3 weeks to see beneficial effects.
- Country of manufacture
- Canada
- Independent testing
- independent labs (Eurofins, Covance)
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Pure Encapsulations
How to take it
Adults: Take 3 capsules daily with a meal, a few hours before or after taking other medications or health products, or as directed by a healthcare practitioner. Drink plenty of water while taking this product. Use for a minimum of 3 weeks to see beneficial effects.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each capsule contains
- DL-Alpha-Lipoic Acid
- 50 mg
- N-AcetylL-cysteine
- 50 mg
- Turmeric Root Extract
- 50 mg
- Milk thistle Seed Extract
- 62.5 mg
- Broccoli Sprout Concentrate
- 50 mg
- Artichoke Leaf Extract
- 62.5 mg
- Taurine
- 112.5 mg
- Glycine
- 112.5 mg
- L-Glutamine
- 112.5 mg
- L-Methionine
- 50 mg
- Chlorella Broken cell
- 100 mg
- Vitamin C
- 4.3 mg
Non-medicinal ingredients
Vegetarian capsule (hypromellose, water).
Free from
Contains no gluten or GMOs.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Pure Encapsulations - Liver-G.I. Detox
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.