Natural Factors Natural Factors - Zymactive Double Strength, 90 tabs

Natural Factors Zymactive Double Strength - A systemic enzyme formula with effective digestive and anti-inflammatory properties. This digestive aid can be used for a wide variety of ailments including arthritis, digestive issues, sports injuries, and immune support. This unique combination of proteolytic enzymes helps break down proteins. These enzymes, including pancreatic enzymes amylase, protease, and lipase, papain from papaya fruit, bromelain from pineapple, and serrapeptase originally isolated from the silkworm, work collectively to offer a broad range of health-promoting benefits. When taken with meals, it helps decrease bloating after high-caloric or high-fat meals. When taken on an empty stomach, it supports anti-inflammation and pain relief. The enteric-coated tablets help protect the proteolytic enzymes, allowing them to pass through the acidic stomach environment intact so they can be released and absorbed in the small intestines.

Natural Factors Natural Factors - Zymactive Double Strength, 90 tabs

Price

Regular Canadian retail price: $46.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.

In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.

See member pricing on Natural Factors Natural Factors - Zymactive Double Strength

Why people keep reordering it

Researched strains
Specific, studied strains at counts high enough to reach your gut.
Guaranteed live cultures
Potency held through the end of shelf life, not just at manufacture.
Digestive balance
Supports regularity, bloating and a healthy gut barrier.

Best suited to: someone bloated after heavy or fatty meals, an athlete sore and swollen after hard sessions, someone who has tried plant-only enzymes without much effect.

What the research supports

An enteric-coated tablet built around pancreatic enzymes and bromelain. The label offers two schedules: one a day with food, or several a day between meals.

Systemic enzyme use has no agreed dose. The label's two schedules differ by purpose: with food for digestion, between meals for the systemic use.

Exercise soreness (evidence: moderate, from randomized controlled trial)
Taken between meals, bromelain has eased measured soreness and swelling after hard workouts and minor strains in several small trials, though results shift with dose and timing.
Meal digestion (evidence: moderate, from randomized controlled trial)
Taken with food, these pancreatic enzymes measurably improve how well a meal's fat, starch and protein break down, scaling with the enzyme units supplied.

Read the literature: Exercise soreness on PubMed, Meal digestion on PubMed.

Is it right for you

Worth it if

someone bloated after heavy or fatty meals
one tablet with the meal adds 40,000 units of protease and amylase to what your own pancreas produces, which is where the heaviness after a large meal comes from.
an athlete sore and swollen after hard sessions
bromelain and papain taken between meals are absorbed intact in small amounts, and bromelain is the one active here with real human trials behind post-exercise soreness.
someone who has tried plant-only enzymes without much effect
this adds concentrated pancreatic enzymes and an enteric coat, so the mix survives the stomach and covers starch, fat and protein rather than protein alone.

Look elsewhere if

vegetarians and anyone avoiding pork
a plant-only blend of bromelain, papain and microbial protease. The pancreatic portion here is porcine, and the label says not to use it if you react to pork proteins.
anyone who reacts to pineapple, papaya or latex
a microbial or fungal enzyme blend, since bromelain and papain come straight from those fruits and cross-react with latex sensitivity.
someone whose main issue is dairy or beans
a targeted lactase or alpha-galactosidase, which act on the specific sugars causing the trouble. Protein-splitting enzymes do not touch those.

What to expect

Taken with a heavy meal, less bloating and heaviness within an hour or two, the same sitting. Taken between meals for recovery, expect nothing dramatic and give it two to three weeks at the three to five tablet schedule before deciding. Swallow whole: chewing breaks the coating and wastes the dose.

How it compares

Compared with a plain bromelain capsule
this stacks serrapeptase, papain and concentrated pancreatin on top, and the enteric coat protects the whole set through the stomach, so it works for meal digestion and between-meal use from one bottle. The tradeoff: bromelain alone carries most of the human evidence, and in a fixed blend you cannot raise it without raising the other five. You also pay more per tablet and cannot take it if pork is off the table.

Product details

Medicinal ingredients
Pancreatic enzymes 10X* (Sus scrofa) (pancreas), Amylase activity 40,000 USP units, Protease activity 40,000 USP units, Lipase activity 3,200 USP units and 1 more
Ingredient form
tabs
Servings per container
90
Suggested use
1 tablet daily with food or as directed by a health care practitioner. Swallow whole, do not chew or crush. For anti-inflammatory and immune function: 1 tablet 3–5 times daily on an empty stomach with water or juice, or as directed by a health care practitioner.
Country of manufacture
Canada
Independent testing
ISURA
Certifications
Non-GMO, Made in Canada
Storage
Store in a cool, dry place
Brand
Natural Factors

How to take it

1 tablet daily with food or as directed by a health care practitioner. Swallow whole, do not chew or crush. For anti-inflammatory and immune function: 1 tablet 3–5 times daily on an empty stomach with water or juice, or as directed by a health care practitioner.

  • Store in a cool, dry place away from direct light.
  • Keep out of reach of children.
  • Consult a practitioner if you are pregnant, nursing or on medication.

Ingredients

Each tablet contains

Pancreatic enzymes 10X* (Sus scrofa) (pancreas)
160 mg
Amylase activity 40,000 USP units
Protease activity 40,000 USP units
Lipase activity 3,200 USP units
Papain (Carica papaya) (fruit) 3,600,000 FCC PU (85.70 mg)
Serrapeptase (Serratiopeptidase, Serratia marcescens [E-15] [whole cell])
10,400 SU (4.70 mg)
Bromelain (Ananas comosus) (pineapple stem) 640,000 FCC PU (19.38 mg)
USP: United States Pharmacopoeia; FCC: Food Chemical Codex; PU: Papain Unit; SU: Serratiopeptidase Unit.

10 times more concentrated than USP standard.

Non-medicinal ingredients

Microcrystalline cellulose, enteric coating (purified water, ethylcellulose, medium chain triglycerides, oleic acid, carbohydrate gum [cellulose], glycerin, sodium alginate, stearic acid), croscarmellose sodium, vegetable grade magnesium stearate (lubricant).

Free from

Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs.

Interactions and cautions

Medications
May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
Timing
If taking antibiotics, separate doses by 2 to 3 hours.
Pregnancy and breastfeeding
Consult a healthcare practitioner before use if pregnant or breastfeeding.
General
Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.

This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.

Questions about Natural Factors - Zymactive Double Strength

Is this the genuine, authentic product?
Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
How is the price below retail?
We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
How fast does it ship?
Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
Can I return it?
You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.