Natural Factors Natural Factors - Vegetarian MacroGest, 60 vcap
Natural Factors Vegetarian MacroGest - Plant Enzyme Formula - Specially designed to support the breakdown of hard-to-digest foods such as beans, whole grains, and vegetables, this full-spectrum, intensive strength enzyme formula is ideal for vegetarian, vegan, and raw food diets providing key enzymes to help break down proteins, carbohydrates, and fats for better nutrient absorption, and to reduce gas production caused by poor digestion of fermentable carbohydrates found in many plant foods. This comprehensive formula also features enzymes that help support a healthy balance of intestinal microflora to keep pathogenic microorganisms in check.

Price
Regular Canadian retail price: $30.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - Vegetarian MacroGest
Why people keep reordering it
- Researched strains
- Specific, studied strains at counts high enough to reach your gut.
- Guaranteed live cultures
- Potency held through the end of shelf life, not just at manufacture.
- Digestive balance
- Supports regularity, bloating and a healthy gut barrier.
Best suited to: eats beans or lentils most days, eating more plants than they used to, vegan or vegetarian avoiding pancreatin, wants protein digestion covered too.
What the research supports
One capsule is a broad digestive enzyme blend built around alpha-galactosidase. The bottle is a 60-day supply at one capsule a day.
Standalone bean-enzyme products dose alpha-galactosidase at 300 to 450 GalU.
- Gas after legumes (evidence: moderate, from randomized controlled trial, crossover trials)
- Alpha-galactosidase breaks down the raffinose and stachyose sugars in beans and lentils that your gut can't digest on its own, the sugars bacteria otherwise ferment into gas. This capsule doses it at full strength.
- Lactose digestion (evidence: strong, from randomized controlled trial)
- Supplemental lactase splits lactose into simple sugars before gut bacteria can ferment it. The effect scales with dose, and the amount here is a fraction of a dedicated lactase tablet.
- General digestion (evidence: limited, from small human trials)
- Broad enzyme blends spread activity across many food types instead of one, but that breadth comes with far less human trial support than a single enzyme matched to a specific food.
Read the literature: Gas after legumes on PubMed, Lactose digestion on PubMed, General digestion on PubMed.
Is it right for you
Worth it if
- Eats beans or lentils most days
- 350 FCC GalU is a full standalone dose of the one enzyme that handles the oligosaccharides in legumes.
- Eating more plants than they used to
- Cellulase at 650 FCC CU and hemicellulase at 1,150 FCC HCU break plant cell walls, which no human enzyme does, so more of what is inside the cell gets released.
- Vegan or vegetarian avoiding pancreatin
- Every enzyme here is fungal, bacterial or fruit-derived, so there is no animal pancreas or ox bile in the capsule.
- Wants protein digestion covered too
- Three separate proteases plus bromelain and papain span the acidic and neutral pH ranges food passes through, rather than working only in one.
Look elsewhere if
- Someone whose issue is dairy
- 1,200 FCC ALU is a small lactase dose. A dedicated lactase tablet at 9,000 FCC ALU taken with the dairy itself is what that job needs.
- Anyone allergic to latex or to fruits like kiwi, banana or pineapple
- The bromelain and papain here cross-react with that allergy pattern. An enzyme blend built without fruit proteases is the safer choice.
- Someone needing help digesting fat
- 270 FCC LU of lipase is light. A formula built around lipase, at several thousand FCC LU, is what fat-heavy meals call for.
What to expect
This works meal by meal, not over weeks. If it helps, you notice less gas and less heaviness after that specific meal, within a few hours. The label direction is one capsule daily with food, so if beans show up at both lunch and dinner, one capsule only covers one of them. The 60 count is two months at the labelled dose.
How it compares
- Compared with a standalone alpha-galactosidase bean enzyme
- You get the same class of legume enzyme dose plus thirteen others, including the cellulase and hemicellulase that plant cell walls need and the proteases that a bean-only product skips. The tradeoff: The single-purpose product is cheaper per capsule and can be taken at every meal that needs it without also dosing you with bromelain and papain.
- Compared with an animal-derived pancreatin enzyme blend
- Fungal and bacterial enzymes stay active across the acidic stomach as well as the small intestine, while pancreatic enzymes only work once the pH turns alkaline, so this one starts digesting sooner. The tradeoff: Pancreatin blends carry far more lipase and often ox bile, so for fat-heavy eating they do more than this does.
Product details
- Medicinal ingredients
- Alpha-amylase (Aspergillus flavus var. oryzae) (whole), Bacterial protease (Bacillus subtilis) (whole cell), Fungal protease (Aspergillus flavus var. oryzae) (whole), Fungal protease (Aspergillus niger) (whole) and 10 more
- Ingredient form
- vcap
- Servings per container
- 60
- Suggested use
- 1 capsule daily with food or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1 capsule daily with food or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetarian capsule contains
- Alpha-amylase (Aspergillus flavus var. oryzae) (whole)
- 76.67 mg (11,500 FCC DU)
- Bacterial protease (Bacillus subtilis) (whole cell)
- 58 mg (58,000 FCC PC)
- Fungal protease (Aspergillus flavus var. oryzae) (whole)
- 40 mg (32,000 FCC HUT)
- Fungal protease (Aspergillus niger) (whole)
- 25.54 mg (115 FCC SAP)
- Diastase (Aspergillus flavus var. oryzae) (whole)
- 20 mg (6,000 FCC DP)
- Glucoamylase (Aspergillus niger) (whole)
- 19.21 mg (23 FCC AGU)
- Lactase (Aspergillus flavus var. oryzae) (whole)
- 12 mg (1,200 FCC ALU)
- Alpha-galactosidase (Aspergillus niger) (whole)
- 11.66 mg (350 FCC GaIU)
- Triacylglycerol lipase (Rhizopus oryzae) (whole)
- 7.72 mg (270 FCC LU)
- Cellulase (Trichoderma longibrachiatum) (whole)
- 3.61 mg (650 FCC CU)
- Bromelain (Ananas comosus) (pineapple stem)
- 3.48 mg (115,000 FCC PU)
- Papain (Carica papaya) (fruit)
- 2.74 mg (115,000 FCC PU)
- Hemicellulase (Aspergillus niger) (whole)
- 1.44 mg (1,150 FCC HCU)
- Invertase (Saccharomyces cerevisiae) (whole)
- 1.15 mg (230 FCC SU)
Non-medicinal ingredients
Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant).
Free from
Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, tree nuts, or GMOs. Suitable for vegetarians/vegans.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- If taking antibiotics, separate doses by 2 to 3 hours.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Vegetarian MacroGest
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.