Natural Factors Natural Factors - Total Body Marine Collagen with Hyaluronic Acid, Glutamine & Biotin, 135 grams
Natural Factors Total Body Marine Collagen with Hyaluronic Acid, Glutamine & Biotin - Features clinically studied Collactive hydrolyzed collagen and elastin with a synergistic combination of nutrients that promote healthy skin, muscles, and connective tissue. Collactive is a 100% marine-based natural ingredient composed of marine collagen and elastin peptides in the same ratio found naturally in human skin. It is formulated specifically for hydration and anti-aging support in the skin dermal layer, and has been shown to reduce the number of wrinkles, including deep wrinkles, within 28 days. Collactive contains hydrolyzed forms of collagen and elastin that are easily absorbed by the body, where they stimulate collagen synthesis and help reduce joint pain associated with osteoarthritis. Collagen and hyaluronic acid work together to provide structure, strength, and resilience in the body’s tissues, and are vital for maintaining hydration in the joints. This formula contains the amino acid L-tryptophan to make it a complete protein with a full spectrum of amino acids and L-glutamine to support protein synthesis and muscle recovery.

Price
Regular Canadian retail price: $49.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Cartilage and connective tissue
- Supports the structures that keep joints moving comfortably.
- Mobility and recovery
- For active bodies and everyday wear alike.
- Skin, hair and nails too
- Collagen support that shows beyond the joints.
Best suited to: wants elastin, not just collagen, wants a light scoop, not protein-sized, taking collagen with a low vitamin c intake, tracking biotin for hair and nails.
What the research supports
Each 2.9 g scoop is built around 2000 mg of marine collagen and elastin, with hyaluronic acid added. The 135 g tub holds about 46 scoops.
Skin and joint trials on collagen peptides typically use 2.5 to 10 g a day.
- Skin elasticity (evidence: moderate, from randomized controlled trial)
- Marine collagen and elastin peptides have placebo-controlled trials measuring shallower wrinkles and better hydrated skin over about four weeks, though the research behind this specific blend is still limited.
- Skin moisture (evidence: moderate, from randomized controlled trial)
- Hyaluronic acid taken by mouth holds water in the skin's outer layers. Most trials use well over twice the 50 mg in one scoop, so expect a smaller effect here.
- Collagen formation (evidence: strong, from mechanistic research, observational studies)
- Vitamin C is required for the enzyme step that assembles new collagen strands. The 60 mg per scoop covers that need without you eating extra fruit.
- Nail strength (evidence: mixed, from small open-label trials)
- Biotin helps the body build the keratin that nails are made from. Trials at this dose show a benefit mainly in people whose diet was already short on it.
Read the literature: Skin elasticity on PubMed, Skin moisture on PubMed, Collagen formation on PubMed, Nail strength on PubMed.
Is it right for you
Worth it if
- Wants elastin, not just collagen
- 120 mg of hydrolyzed elastin per scoop is rare, and elastin is the protein that gives skin its recoil rather than its bulk.
- Wants a light scoop, not protein-sized
- The whole serving is 2.9 g, so it dissolves into a cup of water without the thickness of a 10 g collagen scoop.
- Taking collagen with a low vitamin C intake
- 60 mg of vitamin C per scoop covers the cofactor the hydroxylation enzymes need, which a plain peptide powder leaves you to supply yourself.
- Tracking biotin for hair and nails
- 500 mcg is roughly seventeen times the 30 mcg adequate intake, which is the range the brittle nail studies used.
Look elsewhere if
- Someone chasing gram-level collagen doses
- A plain hydrolyzed collagen peptide powder at 10 g a scoop gives about five times the peptides for less money, though with no elastin, hyaluronic acid or vitamin C.
- Anyone avoiding fish
- Both the collagen and the elastin come from whitefish skin. A bovine hydrolyzed collagen or an eggshell membrane product is the non-marine route.
- Buying it mainly for the glutamine
- 500 mg does very little. Plain L-glutamine powder dosed at 5 g is what the gut and recovery work actually used.
What to expect
Nothing you can feel. The Collactive work is measured on wrinkle counts at 28 days, so a full month of daily scoops is the minimum before judging anything, and the label asks for five months of continuous use for the connective tissue side. The 135 g tub holds about 46 scoops, so one tub roughly covers the 28 day window and nothing longer.
How it compares
- Compared with a plain bovine collagen peptide powder at 10 g a scoop
- This adds hydrolyzed marine elastin, 50 mg hyaluronic acid, 60 mg vitamin C and 500 mcg biotin, none of which a plain peptide tub contains, and the tryptophan fills the one amino acid collagen is missing. The tradeoff: You get about a fifth of the collagen per scoop and pay considerably more per gram of peptide.
- Compared with a standalone oral hyaluronic acid capsule
- One scoop puts the hyaluronic acid, the peptides and the vitamin C cofactor into a single drink instead of three purchases. The tradeoff: 50 mg is less than a dedicated 120 mg hyaluronic acid capsule delivers, so if hydration is the whole reason you are buying, buy it on its own.
Product details
- Medicinal ingredients
- Collactive marine collagen peptide complex, Hyaluronic acid, L-tryptophan, L-glutamine and 2 more
- Ingredient form
- grams
- Suggested use
- 1 serving/scoop (2.9 g) daily or as directed by a health care practitioner. Mix product well in 1–2 cups of liquid (water, juice, etc.) immediately before consumption. For joint pain: Use for a minimum of 5 months to see beneficial effects.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1 serving/scoop (2.9 g) daily or as directed by a health care practitioner. Mix product well in 1–2 cups of liquid (water, juice, etc.) immediately before consumption. For joint pain: Use for a minimum of 5 months to see beneficial effects.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each serving/scoop (2.9 g) contains
- Collactive marine collagen peptide complex
- 2000 mg
- Hydrolyzed collagen (wild-caught North Atlantic whitefish skin)
- 1880 mg
- Hydrolyzed elastin (wild-caught North Atlantic whitefish skin)
- 120 mg
- Hyaluronic acid
- 50 mg
- L-tryptophan
- 100 mg
- L-glutamine
- 500 mg
- Vitamin C (calcium ascorbate, dihydrate)
- 60 mg
- Biotin
- 500 mcg
Non-medicinal ingredients
Organic natural flavour.
Free from
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, shellfish, salt, tree nuts, or GMOs.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Total Body Marine Collagen with Hyaluronic Acid, Glutamine & Biotin
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.