Natural Factors Natural Factors - Glutathione LipoMicel Matrix 300 mg, 60 lsgels
Natural Factors Glutathione LipoMicel Matrix - Delivers an enhanced source of the antioxidant glutathione to protect your body from the oxidative damage caused by free radicals. Glutathione is present within every cell of the body. It is referred to as “the mother of all antioxidants” because it recycles the antioxidants vitamins C and E. Antioxidants like glutathione are considered “anti-agers” as they work to protect the body from the oxidative damage caused by free radicals. Glutathione is rapidly oxidized in the gastrointestinal tract, making standard forms difficult to absorb and use effectively. Natural Factors unique patent-pending technology creates a liquid micelle matrix that disperses the glutathione into tiny micro-droplets, resulting in a highly stable delivery system for higher absorption than standard forms.

Price
Regular Canadian retail price: $32.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - Glutathione LipoMicel Matrix
Why people keep reordering it
Best suited to: someone who has already tried plain glutathione capsules, people who want the antioxidant itself, not a precursor, anyone taking it for a more even skin tone.
What the research supports
Each softgel carries 300 mg of L-glutathione in a LipoMicel matrix. Label range is 1 to 2 a day, so the 60-count bottle lasts 30 to 60 days.
The main human trial used 250 or 1000 mg a day.
- Glutathione stores (evidence: moderate, from randomized controlled trial)
- The gut normally breaks glutathione apart before it reaches the blood, which is why oral doses rarely raise stores much. A six-month trial at 250 to 1000 mg a day raised glutathione in blood and cheek cells, most clearly at the higher dose.
- Skin tone (evidence: limited, from randomized controlled trial)
- Glutathione is thought to divert pigment-making enzymes toward a lighter melanin pathway. A small 12-week trial at 250 mg a day reported a lower melanin index at several measured skin sites.
- Oxidative stress (evidence: mixed, from randomized controlled trial)
- Glutathione is the body's main internal antioxidant, neutralizing unstable molecules that damage cells. Small trials disagree on the markers they move, partly because blood glutathione is a weak stand-in for what is happening inside cells.
Read the literature: Glutathione stores on PubMed, Skin tone on PubMed, Oxidative stress on PubMed.
Is it right for you
Worth it if
- Someone who has already tried plain glutathione capsules
- Standard L-glutathione is largely dismantled in the gut. The micelle suspension is the attempt to get it through intact, and it is the only reason to pay a premium over a plain capsule.
- People who want the antioxidant itself, not a precursor
- This is glutathione delivered ready made, rather than an amino acid your body still has to assemble into glutathione.
- Anyone taking it for a more even skin tone
- The oral glutathione skin trials used 250 to 500 mg a day, which one to two softgels covers directly.
Look elsewhere if
- Vegetarians and vegans
- The softgel shell is gelatin. A vegan capsule glutathione, or a cysteine precursor in a veg capsule, keeps it plant based.
- Anyone on a budget who mainly wants glutathione levels up
- N-acetylcysteine, the cysteine precursor the body builds glutathione from, does that for a fraction of the price and has a longer human research record behind it.
- Someone expecting to feel a difference
- Glutathione has no felt effect at any dose. If daytime energy is what you are chasing, iron status and B vitamins are the more productive place to look first.
What to expect
Nothing perceptible, ever. This is not a supplement with a feel. The trials that found anything measured blood glutathione or skin melanin index over three to six months, so buy it on the reasoning or not at all, and do not judge it by week two.
How it compares
- Compared with N-acetylcysteine
- This supplies glutathione ready made, so it does not depend on your own cysteine supply or on the enzymes that put glutathione together. The tradeoff: NAC costs far less, comes in vegan capsules, and has more human evidence for actually raising glutathione than any oral glutathione product does.
- Compared with a plain reduced L-glutathione capsule
- The micelle matrix is built specifically against the gut breakdown that makes ordinary glutathione capsules a poor bet. The tradeoff: You are paying a premium for a delivery technology whose absorption data comes from the company that owns it, and a standard capsule at three times the milligrams often costs less.
Product details
- Active ingredient
- L-glutathione LipoMicel** Matrix
- Ingredient form
- lsgels
- Strength
- 300 mg
- Servings per container
- 60
- Suggested use
- 1–2 easy-swallow softgels daily or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1–2 easy-swallow softgels daily or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each softgel contains
- L-glutathione LipoMicel** Matrix
- 300 mg
Non-medicinal ingredients
Softgel (gelatin, glycerin, purified water), medium chain triglycerides, xylitol, non-GMO sunflower lecithin, peppermint oil, Stevia rebaudiana leaf.
Free from
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, corn, egg, fish, shellfish, salt, and tree nuts. Tested non-GMO.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Glutathione LipoMicel Matrix
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.