Natural Factors Natural Factors - Double Strength Ultimate Multi Probiotic, 60 vcaps
Natural Factors Double Strength Ultimate Multi Probiotic - 24 billion active cells - A high-potency probiotic formula provides friendly bacteria to support the health of the digestive and genitourinary tracts, a normal immune system, and the gut-brain connection. Ideal for restoring intestinal balance, especially if upset by antibiotic use, poor diet, or stress. Every capsule provides eight strains of lactobacilli for small intestine support and four strains of bifidobacteria for large intestine (colon) support, alongside prebiotics for further support of beneficial bacterial populations. These probiotic strains are carefully selected from human, plant, and dairy sources for their ability to resist gastric acid as well as for optimal absorption and effectiveness. This one-per-day formula provides an easy and convenient way to help restore and maintain a harmonious balance of beneficial bacteria in the gut by inhibiting the colonization and growth of pathogenic organisms that can lead to diarrhea, constipation, bloating, gas, and cramps.

Price
Regular Canadian retail price: $44.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - Double Strength Ultimate Multi Probiotic
Why people keep reordering it
- Researched strains
- Specific, studied strains at counts high enough to reach your gut.
- Guaranteed live cultures
- Potency held through the end of shelf life, not just at manufacture.
- Digestive balance
- Supports regularity, bloating and a healthy gut barrier.
Best suited to: rebuilding gut bacteria after a rough stretch, someone who wants one capsule, not a scoop, people who got nothing from a grocery shelf probiotic.
What the research supports
One capsule delivers 24 billion cfu across twelve probiotic strains. The 60-count bottle lasts two months at one a day.
Single-strain probiotic trials typically use 1 to 10 billion cfu a day.
- Digestive regularity (evidence: moderate, from meta-analysis, randomized controlled trial)
- Lactobacilli and bifidobacteria ferment fibre into short-chain fatty acids that keep stool moving at a steady pace. Meta-analyses of mixed-strain blends like this one report modest gains in frequency and consistency.
- Gut recovery (evidence: moderate, from meta-analysis, randomized controlled trial)
- A stomach bug or a round of medication can wipe out a large share of gut bacteria at once. Multi-strain blends at counts like this are the ones most often trialled for rebuilding those populations afterward.
- Immunity (evidence: limited, from randomized controlled trial)
- Gut bacteria interact with immune cells lining the intestine, but which specific strains matter most is unclear. Effects are strain-specific and inconsistent, which is where a twelve-strain blend at these small individual counts is weakest.
Read the literature: Digestive regularity on PubMed, Gut recovery on PubMed, Immunity on PubMed.
Is it right for you
Worth it if
- Rebuilding gut bacteria after a rough stretch
- Twelve strains covering both the small intestine and the colon is the right shape when you are repopulating broadly rather than targeting one specific complaint.
- Someone who wants one capsule, not a scoop
- The full 24 billion is in a single daily capsule, so there is nothing to mix or measure.
- People who got nothing from a grocery shelf probiotic
- This is several times the count of a typical room temperature capsule, and refrigerated whole cell strains hold their numbers better through the bottle.
Look elsewhere if
- Someone chasing one documented result from one strain
- A single strain product delivering that organism at the count its own trials used will do more than one twelfth of a blend.
- Travellers, or anyone without fridge space
- A shelf stable spore forming probiotic survives a suitcase and a hot car. This one will not.
- Anyone buying it for the prebiotics
- The inulin and FOS in here are carrier level amounts. A dedicated prebiotic fibre at 3 to 5 g a day is what actually feeds a gut population.
What to expect
Stool regularity and gas usually settle over one to two weeks. The first three or four days often bring more gas rather than less as the population shifts, and that normally passes. If it has not changed anything by week four, it is not going to.
How it compares
- Compared with a shelf stable multi-strain probiotic at 1 to 10 billion cfu
- More strains, several times the count, and cold storage means the number you swallow at the end of the bottle is closer to the number on the label. The tradeoff: You have to keep it cold, which rules out travel and any day you forget it in a bag, and it costs more per capsule.
- Compared with a high count single strain product
- Coverage across both bowel segments at once instead of depth in one organism, which suits general maintenance better than a targeted goal. The tradeoff: No individual strain in here reaches the count used in its own research, so if you have a specific outcome in mind you are diluting the very thing you came for.
Product details
- Medicinal ingredients
- Lactobacillus rhamnosus (HA-111) (whole cell) (human), Lactobacillus casei (HA-108) (whole cell) (human), Bifidobacterium breve (HA-129) (whole cell) (human), Lactobacillus plantarum (HA-119) (whole cell) (plant) and 5 more
- Ingredient form
- vcaps
- Servings per container
- 60
- Suggested use
- Take 1 capsule daily or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
Take 1 capsule daily or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetable capsule contains
- 24 billion active cells of the following specially cultured strains of probiotics:
- Lactobacillus rhamnosus (HA-111) (whole cell) (human)
- 2.88 billion cfu
- Lactobacillus casei (HA-108) (whole cell) (human)
- 6 billion cfu
- Bifidobacterium breve (HA-129) (whole cell) (human)
- 2.40 billion cfu
- Lactobacillus plantarum (HA-119) (whole cell) (plant)
- 2.40 billion cfu
- Lactobacillus acidophilus (HA-122) (whole cell) (human)
- 2.40 billion cfu
- Bifidobacterium longum subsp. longum (HA-135) (whole cell) (human)
- 2.40 billion cfu
- Lactobacillus fermentum (HA-179) (whole cell) (dairy)
- 1.20 billion cfu
- Lactobacillus salivarius (HA-118) (whole cell) (human)
- 0.24 billion cfu
- Bifidobacterium bifidum (HA-132) (whole cell) (human)
- 1.20 billion cfu
- Lactobacillus rhamnosus (bifidus) (HA-114) (whole cell) (human)
- 2.40 billion cfu
- Bifidobacterium animalis subsp. lactis (HA-194) (whole cell) (dairy)
- 0.24 billion cfu
- Lactobacillus paracasei (HA-196) (whole cell) (dairy)
- 24 billion cfu
Non-medicinal ingredients
Inulin, fructooligosaccharides (FOS), vegetarian capsule (carbohydrate gum [cellulose], purified water), vegetable grade magnesium stearate (lubricant), silica, ascorbic acid.
Free from
Contains no artificial preservatives, colours or sweeteners; no starch, wheat, gluten, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Refrigeration Required
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- If taking antibiotics, separate doses by 2 to 3 hours.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Double Strength Ultimate Multi Probiotic
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.