Natural Factors Natural Factors - Complete Megazymes, 180 tabs
Natural Factors Complete Megazymes - Vegetarian Formula - Digestive enzymes can do more than aid digestion. Because they are so efficient at breaking down protein, carbohydrates, and fats, they are able to stimulate the good bacteria in the gut, detoxify and cleanse the colon, and therefore improve a number of digestion-related conditions, including food and other allergies. They help to mobilize and expel harmful products from the body. This process occurs at the cellular level, in organs, and in various systems of the body. Natural Factors Complete Megazymes provides a broad spectrum of key digestive enzymes needed for complete digestion. These include amylase to help break down carbohydrates such as starch; lipase to help break down dietary fats; and proteases to help break down proteins in food. Proteolytic enzymes from bromelain and papain also help break down proteins, while supporting a healthy inflammatory response.

Price
Regular Canadian retail price: $22.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - Complete Megazymes
Why people keep reordering it
- Researched strains
- Specific, studied strains at counts high enough to reach your gut.
- Guaranteed live cultures
- Potency held through the end of shelf life, not just at manufacture.
- Digestive balance
- Supports regularity, bloating and a healthy gut barrier.
Best suited to: heavy protein meals sit like a rock, wants a plant and microbial enzyme source, eats large meals and wants room to adjust.
What the research supports
A with-food enzyme tablet built around protease, bromelain and papain. The label ranges from one tablet a day to six, so the 180-tablet bottle lasts one to six months.
Enzyme blends are compared on activity units rather than a research dose. The label's one to six tablets is the range to work within, and people who benefit usually sit nearer the top of it.
- Protein digestion (evidence: strong, from human digestion studies, randomized controlled trial)
- Fungal protease, bromelain and papain measurably break down protein in digestion studies, and protein is the largest single activity in this blend by weight.
- Bloating (evidence: moderate, from randomized controlled trial)
- Multi-enzyme blends taken with high-fat or high-protein meals reduce fullness and bloating in trials, with the clearest effect at higher enzyme activity than one tablet supplies.
- Fat digestion (evidence: moderate, from randomized controlled trial)
- Lipase and amylase break down fat and starch in a dose-dependent way, and the lipase amount here is the part most likely to need doubling up at meals.
Read the literature: Protein digestion on PubMed, Bloating on PubMed, Fat digestion on PubMed.
Is it right for you
Worth it if
- Heavy protein meals sit like a rock
- Protease activity is the bulk of this blend, with fungal protease, bromelain and papain all working on protein from three different angles.
- Wants a plant and microbial enzyme source
- Everything here comes from fungal culture, pineapple stem or papaya fruit, so it avoids the animal pancreatic origin of the most common alternative.
- Eats large meals and wants room to adjust
- 180 tablets and a label range from one to six a day means you can find the amount that works rather than being locked to a fixed dose.
Look elsewhere if
- Bloats after beans, onions or cruciferous vegetables
- There is no cellulase, hemicellulase or alpha-galactosidase in this blend, and alpha-galactosidase is the specific enzyme for those foods. Buy a blend that names it.
- Cannot digest dairy sugar
- No lactase here. A lactase-only tablet taken with the first bite of dairy is cheaper and far more effective for that.
- Allergic to pineapple, papaya or latex
- Bromelain and papain are the two biggest activities in this tablet and the label flags that cross-reactivity directly. A fungal-only enzyme blend avoids both sources.
What to expect
You either notice less heaviness after a large meal within a few days or you do not. This is not a build-up supplement. If three or four heavy meals go by with two tablets each and nothing changes, it is not the right tool and no amount of extra weeks will fix that.
How it compares
- Compared with a pancreatin-based enzyme supplement
- Fungal and plant proteases stay active across a wide pH range, so they start working in the stomach itself rather than waiting for the alkaline environment further down. The tradeoff: At 210 LU per tablet the lipase is the weakest part of this blend, and a concentrated pancreatin product delivers far more fat-digesting activity per pill.
Product details
- Medicinal ingredients
- Enzyme blend, Fungal protease (Aspergillus niger)(whole), Bromelain (Ananas comosus)(pineapple stem), Alpha-amylase (Aspergillus flavus var. oryzae)(whole) and 2 more
- Ingredient form
- tabs
- Servings per container
- 180
- Suggested use
- 1–2 tablets, 1–3 times daily with food or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1–2 tablets, 1–3 times daily with food or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each tablet contains
- Enzyme blend
- 38 mg
- Fungal protease (Aspergillus niger)(whole)
- 13.33 mg (60 FCC SAP)
- Bromelain (Ananas comosus)(pineapple stem)
- 9.09 mg (300,000 FCC PU)
- Alpha-amylase (Aspergillus flavus var. oryzae)(whole)
- 6 mg (900 FCC DU)
- Triacylglycerol lipase (Rhizopus oryzae)(whole)
- 6 mg (210 FCC LU)
- Papain (Carica papaya)(fruit)
- 3.57 mg (150,000 FCC PU)
- FCC: Food Chemical Codex; SAP: Spectrophotometric Acid Protease Unit; PU: Papain Unit; DU: Dextrinizing Unit; LU: Lipase Unit.
Non-medicinal ingredients
Dibasic calcium phosphate dihydrate, microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), stearic acid.
Free from
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- If taking antibiotics, separate doses by 2 to 3 hours.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Complete Megazymes
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.