Natural Factors Natural Factors - Calm Biotic, 30 vcaps
Natural Factors Calm Biotic - An unique formula featuring a specific ratio of two probiotic strains clinically shown to reduce occasional gastrointestinal symptoms due to moderate stress resulting from everyday life. Lactobacillus helveticus and Bifidobacterium longum have been recognized for their ability to modulate mood through their effect on the gut-brain axis and microbiome. Probiotics influence emotional well-being in a variety of ways, including modulating inflammation that can affect brain function, and through effects on brain chemicals such as serotonin. This convenient one-a-day formula provides a guaranteed minimum of 3 billion colony forming units of two proprietary probiotic strains recognized for their ability to reduce stress, moderate general feelings of anxiety, and promote healthy mood balance. These strains are shelf stable and resistant to gastric acid, meaning that they survive to reach the intestine intact, can be taken without food, and do not require refrigeration.
Price
Regular Canadian retail price: $21.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - Calm Biotic
Why people keep reordering it
- Researched strains
- Specific, studied strains at counts high enough to reach your gut.
- Guaranteed live cultures
- Potency held through the end of shelf life, not just at manufacture.
- Digestive balance
- Supports regularity, bloating and a healthy gut barrier.
Best suited to: digestion goes sideways in stressful weeks, wants a probiotic matched to its own research, travels or has no fridge space.
What the research supports
One capsule gives 3 billion CFU split between two strains, R0052 and R0175. The bottle of 30 lasts a month, no fridge needed.
Trials on this exact strain pair use 3 billion CFU a day.
- Digestive comfort (evidence: moderate, from randomized controlled trial)
- Trials of this exact strain pair over 30 days reduced gut symptoms in adults reporting everyday stress, at the same 3 billion CFU dose used here.
- Mood (evidence: moderate, from randomized controlled trial)
- The gut and brain share signalling pathways, and this strain pair is one of the few probiotics tested there directly. Trials found modest improvements in self-rated stress, though the studies are small.
Read the literature: Digestive comfort on PubMed, Mood on PubMed.
Is it right for you
Worth it if
- Digestion goes sideways in stressful weeks
- That specific pattern, gut symptoms that track with stress rather than with food, is what this strain pair was studied against.
- Wants a probiotic matched to its own research
- R0052 and R0175 are named on the panel with individual counts, so you can line the product up against the studies rather than guessing.
- Travels or has no fridge space
- The strains are shelf stable and gastric acid resistant, so the capsule can live in a bag and be taken without food.
Look elsewhere if
- Wants broad general digestive coverage
- Two strains at 3 billion CFU is a narrow tool. A multi-strain formula in the 10 to 50 billion range covers far more ground for everyday regularity and bloating.
- Has an immune-compromised condition
- The label rules out live cultures in that situation. Ask a practitioner about non-live options such as a prebiotic fibre or a heat-treated postbiotic.
- Strictly avoiding dairy
- The L. helveticus strain here is dairy-cultured and the label states it may contain milk and soy. A dairy-free-cultured probiotic avoids that entirely.
What to expect
The trials on this strain pair ran a full 30 days before differences in self-reported stress and digestive comfort showed up, and the bottle holds exactly 30 capsules. Take it every day for the whole month before deciding anything. Nothing will happen in the first week.
How it compares
- Compared with a 50 billion CFU multi-strain probiotic
- This is two named strains at the exact count and ratio their own human trials used, rather than a large count of commonly used species with no matching study behind the specific blend. The tradeoff: It is deliberately narrow. It will not do the general digestive work a broad multi-strain does, and it costs more per capsule than a bulk high-count product.
Product details
- Medicinal ingredients
- Total bacterial culture, Bifidobacterium longum subsp. longum (R0175) (whole cell), (human), 10 and 3 more
- Ingredient form
- vcaps
- Servings per container
- 30
- Suggested use
- 1 capsule daily or as directed by a health care practitioner. If you are on antibiotics, take at least 2–3 hours before or after.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1 capsule daily or as directed by a health care practitioner. If you are on antibiotics, take at least 2–3 hours before or after.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetarian capsule contains
- 3 billion* active cells of the following specially cultured strains of probiotics:
- Total bacterial culture
- 3 billion cfu†
- Bifidobacterium longum subsp. longum (R0175) (whole cell)
- (human)
- 10
- 6 % 0.318 billion cfu†
- Lactobacillus helveticus (R0052) (whole cell)
- (dairy)
- 89
- 4 % 2.682 billion cfu†
cfu: colony forming units
Non-medicinal ingredients
Maltodextrin, vegetarian capsule (carbohydrate gum [cellulose], purified water), vegetable grade magnesium stearate (lubricant).
Free from
Contains no artificial colours, preservatives, or sweeteners; no starch, sugar, wheat, gluten, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Shelf Stable
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- If taking antibiotics, separate doses by 2 to 3 hours.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - Calm Biotic
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.