Natural Factors Natural Factors - BioCoenzymated Methylfolate 1000mcg w/Methylcobalamin Plus Methylcobalamin, 60 sub
Natural Factors BioCoenzymated Methylfolate Plus Methylcobalamin - Features coenzymated forms of folate and vitamin B12, two nutrients needed for normal early fetal development, energy metabolism, red blood cell production, and to help maintain cardiovascular and cognitive health. Preformed coenzyme forms of B vitamins offer immediate, direct nutritional support – even for those with genetic differences that impair metabolism of standard B vitamins. This biocoenzymated formula features EnviroSimplex technology, combining Farm Fresh Factors, an organic whole food blend of land and sea vegetables, with the coenzyme form of the B vitamins. Providing a synergistic phytochemical formula that delivers the most metabolically active nutrients to your cells.
Price
Regular Canadian retail price: $19.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Active methylated forms
- B vitamins in the forms your body can put to use right away.
- Mood and hormone balance
- Supports healthy methylation, mood and hormonal rhythm.
- Energy at the cellular level
- Feeds the pathways behind steady, real energy.
Best suited to: wants a high-dose folate, already covered on b12, prefers folate that needs no conversion, struggles to swallow capsules.
What the research supports
One sublingual tablet gives 1000 mcg of methylfolate and 50 mcg of B12. The bottle of 60 lasts two months.
Studies use 400 mcg to 1 mg of methylfolate a day.
- Heart health (evidence: strong, from randomized controlled trial)
- Folate and B12 both feed the pathway that clears a compound called homocysteine from the blood, and high homocysteine is tied to heart strain. This dose lowers it by a predictable margin in trials.
- Pregnancy (evidence: strong, from randomized controlled trial)
- Folate needs rise before conception and through early pregnancy, and getting enough from food alone is hard. This tablet's 1000 mcg comfortably covers the standing recommendation.
Read the literature: Heart health on PubMed, Pregnancy on PubMed.
Is it right for you
Worth it if
- Wants a high-dose folate, already covered on B12
- 1000 mcg of 5-MTHF is the real content here, and the 50 mcg of B12 rides along without adding much.
- Prefers folate that needs no conversion
- 5-MTHF is already reduced and methylated, so it does not pass through the enzymatic step that turns folic acid into a usable form.
- Struggles to swallow capsules
- It dissolves under the tongue with no water, which is a practical reason to pick it over a capsule.
Look elsewhere if
- Relying on this as their only B12 source
- 50 mcg will not carry someone eating no animal foods. A standalone methylcobalamin at 1000 mcg daily is the right size for that.
- Avoiding lactose
- The tablet base is lactose. A methylfolate in a vegetarian capsule keeps the same active without it.
- Pregnant or planning a pregnancy
- A full prenatal covers folate at the recommended amount and adds the iron, iodine, D3 and DHA this tablet does not carry.
What to expect
Nothing perceptible. Red cell folate turns over slowly and takes roughly 3 to 4 months to fully reflect a change in intake, so this is judged by blood work rather than by feel. The tablet has a faint sweetness from the lactose base and dissolves in about a minute.
How it compares
- Compared with a 1 mg folic acid tablet
- This arrives as the already-reduced 5-MTHF, so it does not depend on the reduction enzyme whose activity varies a lot between people. The tradeoff: Several times the price, and in head to head trials folic acid raises red cell folate just as effectively in people whose conversion is normal.
Product details
- Active ingredient
- Vitamin B12 (methylcobalamin)
- Ingredient form
- sub
- Strength
- 1000 mcg
- Servings per container
- 60
- Suggested use
- : Dissolve 1 tablet daily under the tongue or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
: Dissolve 1 tablet daily under the tongue or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each tablet contains
- Folate (from (6S)-5-methyltetrahydrofolic acid (MTHF), glucosamine salt, Quatrefolic®)
- 1000 mcg
- Vitamin B12 (methylcobalamin)
- 50 mcg
Non-medicinal ingredients
Lactose, microcrystalline cellulose, croscarmellose sodium,, vegetable grade magnesium stearate (lubricant)
Free from
Contains no artificial colours, preservatives, or sweeteners; no starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - BioCoenzymated Methylfolate 1000mcg w/Methylcobalamin Plus Methylcobalamin
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.