Natural Factors Natural Factors - BioCoenzymated Benfotiamine B1 110.3 mg, 60 vcap
Natural Factors BioCoenzymated Benfotiamine B1 - Providing highly bioavailable coenzymated vitamin B1, plus bioactive thiamine diphosphate, alongside Farm Fresh Factors an organic whole food blend of land and sea vegetables. Benfotiamine and sulbutiamine are biologically active forms of thiamine (vitamin B1), a nutrient that is essential for healthy nerve function and for the metabolism of lipids, carbohydrates, and proteins. Ready-to-use benfotiamine and sulbutiamine offer immediate and direct nutritional support, even for those with impaired metabolism.

Price
Regular Canadian retail price: $38.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
See member pricing on Natural Factors Natural Factors - BioCoenzymated Benfotiamine B1
Why people keep reordering it
- Active methylated forms
- B vitamins in the forms your body can put to use right away.
- Mood and hormone balance
- Supports healthy methylation, mood and hormonal rhythm.
- Energy at the cellular level
- Feeds the pathways behind steady, real energy.
Best suited to: wants b1 in a fat-soluble form, eating a high-carbohydrate diet or drinking regularly, working through a practitioner on nerve function.
What the research supports
One vegetarian capsule provides 110.3 mg of vitamin B1 from benfotiamine and sulbutiamine, fat-soluble forms rather than standard thiamine. The bottle holds a two-month supply.
Nerve studies use 300 to 600 mg of benfotiamine a day.
- Nerve comfort (evidence: mixed, from randomized controlled trial)
- Benfotiamine's fat-soluble form crosses into nerve cells that ordinary thiamine struggles to reach. Short trials at 300 to 600 mg daily reported better nerve symptom scores, but longer trials found no benefit.
- Energy (evidence: strong, from human pharmacokinetic study, randomized crossover trial)
- Thiamine is a required cofactor for the enzymes that turn carbohydrate and fat into usable energy. Restoring a real shortfall measurably restores that activity.
Read the literature: Nerve comfort on PubMed, Energy on PubMed.
Is it right for you
Worth it if
- Wants B1 in a fat-soluble form
- Benfotiamine and sulbutiamine bypass the active transport step that limits how much water-soluble thiamine gets absorbed per dose.
- Eating a high-carbohydrate diet or drinking regularly
- Thiamine is consumed in proportion to carbohydrate throughput and is the B vitamin most readily depleted by alcohol.
- Working through a practitioner on nerve function
- The label carries a three-times-daily schedule specifically for that use, which is the only way to reach the amounts the research used.
Look elsewhere if
- Just wants to cover the daily B1 requirement
- Plain thiamine hydrochloride at 100 mg costs a small fraction of this and covers the 1.1 to 1.2 mg requirement many times over.
- Wants the B vitamins working as a group
- A coenzyme B complex gives you the riboflavin, B6, folate and B12 that thiamine shares metabolic pathways with. This bottle is B1 alone.
- Planning to stay on it indefinitely
- The label asks for a practitioner check past 2 months. If you want a maintenance-level B1 you can leave running, take it inside a B complex instead.
What to expect
Nothing you can feel. Thiamine is not a stimulant and does not produce the lift the word energy on a B vitamin label implies. If it is being taken for nerve function under practitioner guidance, the trials measured differences at 3 to 6 weeks.
How it compares
- Compared with plain thiamine hydrochloride or thiamine mononitrate
- Benfotiamine produces substantially higher and longer-lasting thiamine diphosphate in blood than the same oral dose of the water-soluble forms. The tradeoff: Several times the price for a vitamin that most diets already supply, and if all you need is to meet the requirement the cheap form does it just as well.
Product details
- Active ingredient
- Vitamin B1 (benfotiamine, sulbutiamine)
- Ingredient form
- vcap
- Strength
- 110.3 mg
- Servings per container
- 60
- Suggested use
- 1 capsule daily or as directed by a health care practitioner. Bioavailability: 2 capsules daily or as directed by a health care practitioner. Polyneuropathy: 1 capsule 3 times daily or as directed by a health care practitioner. Consult a health care practitioner for use beyond 6 weeks. For all uses except polyneuropathy: Consult a health care practitioner for use beyond 2 months.
- Country of manufacture
- Canada
- Independent testing
- ISURA
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Natural Factors
How to take it
1 capsule daily or as directed by a health care practitioner. Bioavailability: 2 capsules daily or as directed by a health care practitioner. Polyneuropathy: 1 capsule 3 times daily or as directed by a health care practitioner. Consult a health care practitioner for use beyond 6 weeks. For all uses except polyneuropathy: Consult a health care practitioner for use beyond 2 months.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetarian capsule contains
- Vitamin B1 (benfotiamine, sulbutiamine)
- 110.3 mg
Non-medicinal ingredients
Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), stearic acid.
Free from
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or genetically modified genes or proteins. Suitable for vegetarians/vegans.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Natural Factors - BioCoenzymated Benfotiamine B1
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.