Natural Factors Natural Factors - Alpha-Lipoic Acid w/ B1 & B2 - 600 mg, 60 vcap

Price

Regular Canadian retail price: $25.48 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.

Currently out of stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.

See member pricing on Natural Factors Natural Factors - Alpha-Lipoic Acid w/ B1 & B2 - 600 mg

Why people keep reordering it

Year-round defense

Daily support for a resilient immune response.

Antioxidant support

Helps protect cells from everyday oxidative stress.

Tradition meets research

Time-tested ingredients in clinically informed doses.

Best suited to: want the dose the research actually used, looking at ala for nerve comfort, watching blood sugar alongside diet changes, already taking ala on its own.

What the research supports

One capsule provides 600 mg of alpha-lipoic acid alongside 25 mg of thiamine and 2.5 mg of riboflavin. The bottle holds a two-month supply.

Studies use 600 mg of ALA a day.

Nerve comfort (evidence: moderate, from randomized controlled trial, meta-analysis)

ALA is thought to protect nerve tissue from oxidative stress that impairs signaling. Trials at 600 mg daily against placebo report real but modest drops in burning, tingling and numbness.

Antioxidant capacity (evidence: moderate, from randomized controlled trial, meta-analysis)

Lipoic acid both quenches free radicals itself and regenerates vitamin C, vitamin E and glutathione back to their active forms, so its effect shows up in markers well beyond lipoic acid itself.

Glucose uptake (evidence: mixed, from randomized controlled trial, meta-analysis)

ALA is thought to help cells respond to insulin so more glucose moves out of the blood and into tissue. Trials on oral ALA report modest changes in fasting glucose in some people and none in others.

Energy (evidence: strong, from established nutrition science)

Thiamine and riboflavin are required cofactors in the enzyme steps that turn carbohydrate and fat into usable energy. Running low on either can leave you eating enough but still feeling flat.

Read the literature: Nerve comfort on PubMed, Antioxidant capacity on PubMed, Glucose uptake on PubMed, Energy on PubMed.

Is it right for you

Worth it if

Want the dose the research actually used

600 mg in a single capsule matches the daily amount across the oral ALA trials, with no stacking of two or three capsules to get there.

Looking at ALA for nerve comfort

600 mg daily is the amount used in the randomized trials that measured burning and tingling sensations in the hands and feet.

Watching blood sugar alongside diet changes

ALA is studied for how efficiently cells pull glucose in, and the label's own warning about low blood sugar signs tells you it does something measurable there.

Already taking ALA on its own

The thiamine and riboflavin cover the two vitamins that partner ALA inside the same enzyme complexes, which a standalone ALA capsule leaves out.

Look elsewhere if

Anyone shopping for a B-complex

This carries two of the eight B vitamins, and at 2.5 mg the riboflavin is barely above a day's requirement. Buy an actual B-complex if that is the goal.

Someone who specifically wants R-lipoic acid

A panel that reads plain alpha-lipoic acid means the racemic mix, so roughly half of the 600 mg is the R form. Look for sodium R-lipoate on the panel if you want R only.

Only remembers pills mid-meal

Food cuts ALA absorption by around 30 percent, so if dinner is the only slot this will realistically happen, a nutrient less fussy about timing is a better use of the money.

What to expect

Nothing you can feel in week one. The trials that measured changes in nerve sensation ran three weeks at the shortest and three months more often, so give it that long before deciding. If you get sweating, shakiness, chills or confusion, that is the blood sugar effect, and it means stop and speak to a practitioner.

How it compares

Compared with a plain alpha-lipoic acid capsule with no B vitamins

Same 600 mg of ALA, plus 25 mg of thiamine and 2.5 mg of riboflavin, which are the vitamins working beside lipoic acid in the pyruvate dehydrogenase complex. The tradeoff: You pay for two B vitamins a multivitamin may already be covering, and 2.5 mg of riboflavin is a token amount rather than a therapeutic one.

Compared with R-lipoic acid or sodium R-lipoate

This is the racemic form at a full 600 mg, which is the exact form and dose the human trial record actually sits on. The tradeoff: R-lipoic acid is the biologically active half and absorbs better per milligram, so you need less of it. It costs considerably more, and its own trial evidence is thinner than the pile behind plain 600 mg.

Product details

Medicinal ingredients

Alpha-lipoic acid, Vitamin B1 (thiamine hydrochloride), Vitamin B2 (riboflavin)

Ingredient form

vcap

Strength

600 mg

Servings per container

60

Suggested use

Take 1 capsule daily or as directed by a health care practitioner.

Country of manufacture

Canada

Independent testing

ISURA

Certifications

Non-GMO, Made in Canada

Storage

Store in a cool, dry place

Brand

Natural Factors

How to take it

Take 1 capsule daily or as directed by a health care practitioner.

• Store in a cool, dry place away from direct light.
• Keep out of reach of children.
• Consult a practitioner if you are pregnant, nursing or on medication.

Ingredients

Non-medicinal ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), dibasic calcium phosphate dihydrate, silica, stearic acid.

Free from

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Interactions and cautions

Medications

Some immune botanicals may interact with immunosuppressant medication. Review with your practitioner.

Timing

Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.

Pregnancy and breastfeeding

Consult a healthcare practitioner before use if pregnant or breastfeeding.

General

Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.

This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.

Questions about Natural Factors - Alpha-Lipoic Acid w/ B1 & B2 - 600 mg

Is this the genuine, authentic product?

Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.

How is the price below retail?

We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.

How fast does it ship?

Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.

Can I return it?

You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.