Genestra Genestra - Butyrate Complex 460 mg, 90 vcaps
Genestra Butyrate Complex - Butyrate is an important short-chain fatty acid (SCFA) that is naturally produced within the large intestine and considered an important source of energy for the epithelial cells that line it. One of the key functions of the large intestine is the absorption of water and nutrients that were unable to be absorbed during earlier digestion. The bacteria present within the large intestine also help to break down undigested food matter, such as dietary fibre. Most butyrate in the large intestine is formed when bacteria ferments or breaks down dietary fibre into butyrate and other SCFAs. Butyrate is also a source of energy for the rest of the body: it’s estimated that SCFAs can contribute as much as 5-15% of the total daily caloric requirements of humans.

Price
Regular Canadian retail price: $51.58 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
Currently out of stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Meaningful EPA and DHA
- Real doses of the fats most diets fall short on, not a token amount.
- Purified for freshness
- Distilled to remove heavy metals and keep it fresh, with no fishy aftertaste.
- Heart, brain and joints
- The essential fats behind how you think, move and recover.
Best suited to: someone with low dietary fibre intake right now, someone rebuilding gut lining support after a rough digestive stretch, people who want a capsule dosed with meals, not a powder.
What the research supports
Each capsule delivers 460 mg of butyric acid as calcium and magnesium butyrate, taken three times daily with meals. The bottle of 90 lasts a month.
Gut studies on butyrate salts commonly use 600 to 1500 mg a day.
- Colon cells (evidence: moderate, from human clinical trials, mechanistic studies)
- Butyrate is the fuel colon cells prefer to burn for energy, ahead of sugar or other fats. Human studies using oral butyrate salts show it reaches the colon and is taken up by these cells.
- Gut comfort (evidence: limited, from small human trials, animal studies)
- A well fed, well fuelled gut lining is thought to hold together better and let less through it shouldn't. Small human trials on oral butyrate suggest a comfort benefit, but the evidence base is thin compared to fibre research.
Read the literature: Colon cells on PubMed, Gut comfort on PubMed.
Is it right for you
Worth it if
- Someone with low dietary fibre intake right now
- Butyrate is normally made by fermenting fibre in the colon, so if fibre intake is low, direct butyrate supplementation covers that gap.
- Someone rebuilding gut lining support after a rough digestive stretch
- Butyrate is the primary energy source for the cells lining the large intestine.
- People who want a capsule dosed with meals, not a powder
- 460 mg per vegetable capsule taken three times daily with food is straightforward to fit around eating.
Look elsewhere if
- Someone eating a high-fibre diet already producing plenty of butyrate
- Keep eating the fibre. Your own bacteria make butyrate from it continuously, and a supplement is for people whose intake or gut flora is not doing that job.
What to expect
There's nothing to feel in the way of energy or mood. Any change would show up as steadier digestion or bowel regularity over several weeks of consistent use, since this is feeding gut lining cells rather than acting acutely.
How it compares
- Compared with increasing fermentable fibre intake (like inulin or resistant starch)
- This delivers butyrate itself directly, bypassing the fermentation step entirely, so effects don't depend on your gut bacteria's fermenting capacity. The tradeoff: You lose the broader prebiotic effect that feeding fibre to gut bacteria provides, since this doesn't feed the microbiome the way fibre does.
- Compared with sodium butyrate supplements
- Using calcium and magnesium as the mineral pairing avoids adding sodium, which matters for anyone watching sodium intake. The tradeoff: You're getting extra calcium and magnesium alongside the butyrate, which is a non-issue for most people but worth noting if you're already tracking those minerals closely.
Product details
- Active ingredient
- Butyric acid (calcium/magnesium butyrate)
- Ingredient form
- vcaps
- Strength
- 460 mg
- Servings per container
- 90
- Suggested use
- : Take 1 capsule 3 times daily with meals or as directed by a health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- independent labs (NSF GMP-certified facility)
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- Genestra
How to take it
: Take 1 capsule 3 times daily with meals or as directed by a health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each vegetable capsule contains
- Butyric acid (calcium/magnesium butyrate)
- 460 mg
Non-medicinal ingredients
Hypromellose, hyprolose, cellulose
Free from
Contains no gluten, yeast, wheat, sodium, sugar, dairy, artificial colouring or flavouring. Vegan, Non-GMO.
Interactions and cautions
- Medications
- May add to the effect of blood-thinning medication. Review with your practitioner if you take anticoagulants.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about Genestra - Butyrate Complex
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.