AOR AOR - SAMe 400, 60 tab
AOR SAMe 400 - S-Adenosyl-L-Methionine (SAMe) is a natural compound and methyl group donor that supports the methylation cycle, a process which is essential for many aspects of health. Methylation is fundamental for ridding the body of certain toxins, and certain people, such as those with chronic liver disorders, cannot produce adequate levels of SAMe. SAMe’s effectiveness to support a balanced mood is demonstrated by many clinical studies. SAMe is in fact so effective for boosting a low mood that it is legally registered as a prescription drug in several European countries for mood balance. It is thought that SAMe works by helping to boost serotonin, dopamine and melatonin levels in the brain, low levels of which are commonly associated with mood imbalances such as anxiety and depression. SAMe has also been found to support joint health in osteoarthritis patients as effectively as a popular anti-inflammatory drug by reducing inflammation and protecting joint tissue from degradation.

Price
Regular Canadian retail price: $116.98 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $75. 30-day returns. Ships from Victoria, BC.
Why people keep reordering it
- Adaptogen support
- Herbs traditionally used to help the body adapt to everyday stress.
- Steady energy
- Supports balanced energy without the spike and the crash.
- Calm focus
- Helps you stay even through demanding days.
Best suited to: stress resilience, steady energy, calm focus, adrenal support.
What the research supports
- Handle stress better (evidence: moderate, from rct, systematic review)
- Adaptogens like ashwagandha help you feel less frazzled on busy days.
- Steadier energy (evidence: mixed, from clinical trial)
- Some people feel more even energy and less fatigue, though results vary.
Read the literature: Handle stress better on PubMed, Steadier energy on PubMed.
Product details
- Active ingredient
- AOR - SAMe 400
- Ingredient form
- tab
- Strength
- See product label
- Servings per container
- 60
- Suggested use
- As directed on label
- Country of manufacture
- Canada
- Independent testing
- ISO-certified third-party labs
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- AOR
How to take it
Take 1 to 2 capsules daily with food, or as directed by your healthcare practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Interactions and cautions
- Medications
- May interact with thyroid, sedative or immune medication. Review with your practitioner.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about AOR - SAMe 400
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- Forty-two years of supplier relationships let us price below what stores charge. You see it privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 2pm ET ship the same business day from our Canadian warehouse. Shipping is free over $75.
- Can I return it?
- Unopened products can be returned within 30 days. Find it cheaper anywhere in Canada and we will match the price.