AOR AOR - Maxmethyl, 90 vcaps
AOR MaxMethyl - An excellent supplement for aging in general, for those who know they have high homocysteine levels, and those looking for support against age-related degenerative conditions of the bones, joints, nerves and cognitive function. Contains all the cofactors and methyl donors needed to promote methylation and convert homocysteine into useful amino acids: vitamin B6, vitamin B12, folate and trimethylglycine (TMG). This combination of nutrients was shown to significantly reduce homocysteine levels after just 6 weeks of supplementation. Methylation is a key process that is essential for the function of every cell in the body, keeping aging and disease at bay. Methylation reduces homocysteine, a toxic amino acid that dramatically increases the risk of heart disease, cancer, bone loss, joint degradation, mood imbalances and cognitive decline.

Price
Regular Canadian retail price: $33.88 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Active methylated forms
- B vitamins in the forms your body can put to use right away.
- Mood and hormone balance
- Supports healthy methylation, mood and hormonal rhythm.
- Energy at the cellular level
- Feeds the pathways behind steady, real energy.
Best suited to: has tested homocysteine levels above normal range, has an mthfr variant and avoids folic acid, wants b vitamins in already-active forms.
What the research supports
Each capsule pairs active-form B vitamins with 500 mg of TMG (betaine). Three capsules a day, so the 90-count bottle lasts a month.
Studies use 1 to 6 g of TMG a day.
- Heart health (evidence: moderate, from randomized controlled trial)
- A compound called homocysteine builds up when the body runs short of methyl donors to clear it. B12, folate, B6 and TMG each supply a piece of that reaction, and high homocysteine is tied to heart strain.
Read the literature: Heart health on PubMed.
Is it right for you
Worth it if
- has tested homocysteine levels above normal range
- the combination of TMG, methylcobalamin, L-5-MTHF and P5P is the same nutrient set used in trials that lowered homocysteine within six weeks.
- has an MTHFR variant and avoids folic acid
- the folate here is calcium L-5-MTHF, the already-active form that doesn't require the MTHFR enzyme to convert.
- wants B vitamins in already-active forms
- P5P, methylcobalamin and L-5-MTHF skip the conversion steps that synthetic B6, B12 and folic acid require.
Look elsewhere if
- just wants a basic daily multivitamin
- a standard multi covers general B vitamin needs without this product's homocysteine-specific focus and three-times-daily schedule.
- has liver or cardiovascular disease
- this needs a health care practitioner's input first, since the label specifically flags those conditions before use.
- wants once-a-day convenience
- look for a single-capsule methylation formula, since this one is dosed three times a day to maintain steady TMG intake.
What to expect
Homocysteine-lowering studies using this type of nutrient combination showed measurable drops within six weeks, so blood work is the realistic way to see a change, not how you feel day to day. There's no immediate sensation to expect since this is a background metabolic process, not a stimulant or sleep aid.
How it compares
- Compared with a plain B-complex with folic acid and cyanocobalamin
- MaxMethyl uses pre-activated B6, B12 and folate plus a meaningful TMG dose, giving the body methyl donors it doesn't have to convert first. The tradeoff: it costs more and requires three capsules a day instead of one.
- Compared with TMG powder taken alone
- this bundles TMG with the B vitamin cofactors it needs to actually drive methylation, rather than relying on TMG by itself. The tradeoff: you get less TMG per serving than you'd get dosing straight powder to bowel tolerance.
Product details
- Medicinal ingredients
- Vitamin B6 (pyridoxal-5-phosphate), Folic acid (calcium L-5-MTHF), Vitamin B12 (methylcobalamin), Trimethylglycine (betaine anhydrous)
- Ingredient form
- vcaps
- Servings per container
- 90
- Suggested use
- Adults: Take one capsule three times daily with or without food, or as directed by a qualified health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISO-certified third-party labs
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- AOR
How to take it
Adults: Take one capsule three times daily with or without food, or as directed by a qualified health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each capsule contains
- Vitamin B6 (pyridoxal-5-phosphate)
- 17mg
- Folic acid (calcium L-5-MTHF)
- 267mcg
- Vitamin B12 (methylcobalamin)
- 216mcg
- Trimethylglycine (betaine anhydrous)
- 500mg
Non-medicinal ingredients
Capsule: hypromellose.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about AOR - Maxmethyl
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.