AOR AOR - I-3-C Indole-3 Carbinol 200mg, 60 vcaps
AOR I-3-C Indole-3 Carbinol - A phytonutrient found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and bok choi. I-3-C has been shown to shift the balance of metabolic enzymes that process estrogens thereby reducing the formation of “bad” estrogens and increasing the formation of “good” estrogens. Human studies in women taking I-3-C have shown a favourable shift in estrogen metabolism, and I-3-C has been shown to be protective against estrogen dominance. Estrogen dominance has been linked to fibroids, breast tenderness, premenstrual syndrome, endometriosis and other women’s health concerns. Women who are concerned with safer estrogen metabolism, who have a family history or increased risk of estrogen-dependent cancers, or those that have a higher ratio of bad to good estrogens can benefit from this product. I-3-C may also be a beneficial supplement for those who want to reap some of the benefits of Brassica vegetables but have difficulty eating them raw.

Price
Regular Canadian retail price: $35.88 CAD. Price Vault members pay below retail on this product. Member pricing is private and shown after a free opt-in, with no membership fee, no minimum order and no subscription.
In stock. Free shipping across Canada on orders over $89, flat $9.95 under that. 30 days to request a return, with return shipping paid by the customer. Ships from Victoria, BC.
Why people keep reordering it
- Active methylated forms
- B vitamins in the forms your body can put to use right away.
- Mood and hormone balance
- Supports healthy methylation, mood and hormonal rhythm.
- Energy at the cellular level
- Feeds the pathways behind steady, real energy.
Best suited to: wants a favourable estrogen metabolite ratio, family history of estrogen-related concerns, dislikes eating raw broccoli or cabbage daily.
What the research supports
Each capsule delivers 200 mg of indole-3-carbinol (I3C), a compound found in cruciferous vegetables like broccoli. The 60-capsule bottle lasts one to two months.
Studies on estrogen metabolite shifts use 200 to 400 mg a day.
- Estrogen metabolism (evidence: moderate, from small human trials, mechanistic studies)
- I3C shifts liver enzymes toward an estrogen breakdown pathway linked to a more favourable metabolite ratio. Human trials at 200 to 400 mg daily show this shift occurs reliably.
Read the literature: Estrogen metabolism on PubMed.
Is it right for you
Worth it if
- Wants a favourable estrogen metabolite ratio
- 200 mg of I3C per capsule is dosed in the range shown in human studies to shift estrogen metabolism toward the 2-hydroxy pathway.
- Family history of estrogen-related concerns
- I3C's effect on estrogen metabolism is the specific reason this ingredient gets used by people managing that kind of risk.
- Dislikes eating raw broccoli or cabbage daily
- This delivers a standardized dose of the same compound those vegetables provide without needing to eat them raw in quantity.
Look elsewhere if
- Anyone with symptoms of low estrogen
- instead consult a practitioner before adding anything that shifts estrogen metabolism further, since I3C is not the right direction for that picture.
- Pregnant or breastfeeding
- look for a different approach entirely, since this product is not meant for use during pregnancy or lactation.
- Trying to conceive or has a liver condition
- talk to a practitioner first, since I3C's effect on hormone metabolism and liver enzymes makes this one to clear with someone who knows your history.
What to expect
Shifts in estrogen metabolite ratios have been measured in study participants within weeks of consistent daily use, but this is not something you feel directly like an energy or mood effect. It's a background metabolic change, not a sensation.
How it compares
- Compared with eating more raw cruciferous vegetables
- This gives a fixed 200 mg dose of I3C per capsule without needing large, consistent servings of raw broccoli, cabbage or Brussels sprouts. The tradeoff: You lose the fibre, vitamins and other phytonutrients whole vegetables provide alongside the I3C.
- Compared with DIM (diindolylmethane)
- I3C is the precursor compound found directly in the vegetable, and this converts to DIM and other metabolites in the stomach after ingestion. The tradeoff: Conversion to DIM varies somewhat by person, whereas a DIM supplement delivers that downstream compound directly.
Product details
- Active ingredient
- Indole-3-Carbinol (I3C)
- Ingredient form
- vcaps
- Strength
- 200mg
- Servings per container
- 60
- Suggested use
- Adults: Take one capsule one to two times daily with or without food, or as directed by a qualified health care practitioner.
- Country of manufacture
- Canada
- Independent testing
- ISO-certified third-party labs
- Certifications
- Non-GMO, Made in Canada
- Storage
- Store in a cool, dry place
- Brand
- AOR
How to take it
Adults: Take one capsule one to two times daily with or without food, or as directed by a qualified health care practitioner.
- Store in a cool, dry place away from direct light.
- Keep out of reach of children.
- Consult a practitioner if you are pregnant, nursing or on medication.
Ingredients
Each capsule contains
- Indole-3-Carbinol (I3C)
- 200mg
Non-medicinal ingredients
Microcrystalline cellulose. Capsule: hypromellose.
Interactions and cautions
- Medications
- May interact with certain prescription medications. Review with your pharmacist if you take daily medication.
- Timing
- Separate from medications by 2 to 4 hours unless directed otherwise by a healthcare practitioner.
- Pregnancy and breastfeeding
- Consult a healthcare practitioner before use if pregnant or breastfeeding.
- General
- Use only as directed. Discontinue and consult a practitioner if you experience an adverse reaction.
This product is not intended to diagnose, treat, cure or prevent disease. Consult a healthcare practitioner before use. Free certified advisors are available at 1-888-386-1211, Mon to Fri, 9am to 5pm PT.
Questions about AOR - I-3-C Indole-3 Carbinol
- Is this the genuine, authentic product?
- Yes. It is identical to what you would pay full price for anywhere else, sourced through our authorized supplier relationships.
- How is the price below retail?
- We buy direct, with nobody in the middle taking a cut, and we sell it for close to what we paid. You see the price privately because you have unlocked the Vault.
- How fast does it ship?
- Orders placed before 12pm PT are processed the same day and ship within two business days. Shipping is free over $89, and a flat $9.95 under that.
- Can I return it?
- You have 30 days after it arrives to request a return. Product must be unused, in its original packaging, with proof of purchase, and return shipping is paid by you. Find it cheaper anywhere in Canada and we will match the price.